
Leaving pizza out overnight is a common occurrence, but is it safe? The answer is a little more complicated than a simple yes or no. Pizza is considered a perishable food item, and if left out, can cause bacteria to grow, leading to possible foodborne illnesses. The USDA and food safety specialists recommend following the 2-hour rule, meaning that if pizza has been left out at room temperature for more than two hours, it should not be consumed. However, some people have consumed pizza that has been left out overnight without any consequences, and some experts argue that the 2-hour rule may be overly conservative. Ultimately, it is a judgement call, but to stay on the safe side, it is recommended to refrigerate leftover pizza within two hours and reheat it before consuming.
| Characteristics | Values |
|---|---|
| Safe to eat if left out | No |
| Safe period | 2 hours |
| Safe temperature range | 40°F to 140°F |
| Safe period at above 90°F | 1 hour |
| Safe period for reheating | 6 hours |
| Safe storage | Refrigerate or freeze |
| Safe storage temperature | 40°F or below |
| Safe storage duration | 3-4 days |
| Safe freezing duration | 1-2 months |
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What You'll Learn
- Pizza should be refrigerated within two hours to prevent bacterial growth
- Bacteria on pizza can cause foodborne illnesses, including food poisoning
- Pizza can be safely stored in the fridge for three to four days
- Pizza can be frozen to extend its shelf life beyond four days
- Reheating pizza can kill some bacteria

Pizza should be refrigerated within two hours to prevent bacterial growth
Pizza is a perishable food, and if left out, it can cause bacteria to grow and lead to possible foodborne illnesses. The USDA's 2-hour rule should be followed for pizza and other perishable foods. If pizza has been at room temperature for more than two hours, it should not be consumed. Perishable foods like pizza should not sit out for more than an hour if the temperature is above 90°F. Any bacteria present on leftover pizza can grow rapidly in the danger zone between 40°F and 140°F, and can double in number in as little as 20 minutes. This means that if you eat pizza that has been sitting out, you are increasing your risk of being exposed to foodborne pathogens and the possibility of coming down with a foodborne illness.
Bacteria like Salmonella, E. coli, Campylobacter, and Listeria can grow on pizza while it sits out. Even ingesting a small amount of spoiled food can be bad for your digestive system and cause severe dehydration, requiring hospitalization. Food safety rules say that food can only be kept in the temperature range of 40°F to 140°F for two hours. After that, food in the danger zone can become dangerous to eat. Pizza must be taken out of the danger zone after two hours because it contains ingredients with low thresholds for bacterial growth, such as cheese, tomato products, meat, and cut veggies.
To avoid the risk of foodborne illness, leftover pizza should be refrigerated within two hours and can be reheated the next day. Refrigerated pizza can be kept for three to four days, according to the USDA and FDA. If you are worried about bacteria but still want to eat the pizza, you can reheat it in the oven or microwave, as this can help kill some bacteria.
Some people may argue that leaving pizza out overnight is not the worst thing in the world, and it is ultimately a judgment call. However, it is important to note that foodborne illnesses can take weeks to show up, so you might not make the connection between the illness and the pizza. It is always better to be safe than sorry and refrigerate your pizza within two hours to prevent bacterial growth.
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Bacteria on pizza can cause foodborne illnesses, including food poisoning
Pizza is considered a perishable food item. If left out, it can cause bacteria to grow and lead to possible foodborne illnesses. Foodborne illnesses can be caused by pathogens (viruses, bacteria, or parasites) in contaminated food or drink. The incubation period for foodborne illnesses can range from several hours to a week, so it can be difficult to connect your illness to the pizza you ate.
Bacteria like Salmonella, E. coli, Campylobacter, and Listeria can grow on pizza while it is left out. These bacteria can cause food poisoning, leading to serious digestive symptoms and bacterial infections. Food poisoning can cause flu-like symptoms such as fever, chills, vomiting, and sweating. It can also lead to severe dehydration that may require hospitalization.
The U.S. Department of Agriculture advises that pizza should not be left out at room temperature for more than two hours to prevent bacterial growth in the "danger zone," between 40–140°F. At these temperatures, any bacteria present on the pizza can double in number in as little as 20 minutes. If the temperature is above 90°F, perishable food should not be left out for more than an hour.
To reduce the risk of foodborne illnesses, refrigerate leftovers as soon as possible. Place leftover pizza in an airtight container or wrap it tightly, then store it in the fridge. Leftovers, including pizza, can be kept in the fridge for three to four days. You can also freeze pizza to keep it safe from bacterial growth. However, for the best flavor and texture, it is recommended to eat frozen pizza within three months.
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Pizza can be safely stored in the fridge for three to four days
Pizza is a perishable food that should not be left out at room temperature for more than two hours, according to food safety guidelines. If left out for longer, bacteria such as Staphylococcus aureus, E. coli, Salmonella, Campylobacter, and Listeria can grow on the pizza, increasing the risk of foodborne illnesses.
Therefore, it is essential to store leftover pizza properly to prevent bacterial growth and maintain food safety. The best way to do this is to refrigerate it within two hours of cooking or purchasing. When storing pizza in the fridge, it is recommended to wrap each slice individually in aluminum foil, wax, or parchment paper to prevent dehydration. Place the wrapped slices in an airtight container or seal them tightly with plastic wrap to further extend their shelf life.
It is worth mentioning that reheating leftover pizza can kill some bacteria and reduce the risk of foodborne illness. However, it is crucial to ensure that the pizza is heated thoroughly to a temperature that kills bacteria. Reheating pizza in the oven or microwave is a common practice.
In conclusion, pizza lovers can safely enjoy their leftover slices by following proper storage and reheating techniques. By refrigerating pizza within two hours and consuming it within three to four days, the risk of foodborne illness is significantly reduced.
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Pizza can be frozen to extend its shelf life beyond four days
Pizza is a perishable food, and if left out, it can cause bacteria to grow and lead to possible foodborne illnesses. The United States Department of Agriculture (USDA) recommends following the "
The temperature range of 40°F to 140°F is often called "the danger zone" because this is the optimum window for dangerous bacterial growth, which can cause foodborne illnesses. After eight hours or more in this temperature range, bacteria on your pizza will multiply rapidly, and your pizza will be teeming with harmful bacteria.
To avoid this, leftover pizza should be stored in an airtight container or wrapped tightly before being placed in the fridge, where it can be kept for three to four days, according to the USDA.
However, if you want to extend the shelf life of your pizza beyond four days, freezing is a great option. Freezing leftover pizza can keep those slices safe to eat for quite a while, and it's a handy way to ensure you don't waste any extra pizza. When freezing pizza, it's important to use an airtight container or wrap each slice individually in plastic wrap or aluminum foil to avoid freezer burn.
While pizza can be safely frozen and consumed beyond this timeframe, it is recommended to consume it within one to three months for the best flavor and texture. After thawing, pizza can be stored in the refrigerator for a few days before reheating and consuming. There are various ways to reheat pizza, including using an oven, air fryer, frying pan, microwave, or toaster oven.
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Reheating pizza can kill some bacteria
Pizza is a perishable food that can cause bacteria to grow and lead to possible foodborne illnesses. The USDA's Food Safety and Inspection Service recommends that perishable foods should not be consumed if they have been at room temperature for more than two hours. This is because bacteria can grow rapidly at room temperature, increasing the risk of foodborne illnesses.
However, reheating pizza can kill some bacteria and reduce the risk of foodborne illnesses. It is important to note that reheating pizza may not kill all bacteria, and the effectiveness of killing bacteria depends on the reheating method and temperature. For example, heating pizza in a microwave for a full minute can kill most bacteria, but some may survive due to uneven heating.
To ensure food safety, it is recommended to refrigerate leftover pizza within two hours and reheat it properly before consumption. The best way to reheat pizza and kill bacteria is to use an oven, air fryer, or stove. When using an oven, preheat it to 350 degrees Fahrenheit and cook the pizza on a foil-lined tray for about 10 minutes. This ensures that the pizza is heated evenly and kills most bacteria.
Another effective method is to use an air fryer. Preheat the air fryer to 350 degrees Fahrenheit and cook the pizza for 3-5 minutes, checking frequently to ensure even cooking. Reheating pizza in an air fryer can be quick and efficient, but it is important to monitor the cooking process to avoid burning.
Using a stove is also a recommended method for reheating pizza and killing bacteria. Preheat a nonstick pan over medium-low heat, place the pizza in the pan, and cook until the bottom is crisped up. Then, increase the heat to medium, add a small amount of water to create steam, and cover the pan with a lid. This method ensures even heating and helps kill bacteria.
It is important to note that while reheating pizza can kill some bacteria, it is always best to practice proper food handling and storage to prevent foodborne illnesses. Leftover pizza should be stored in an airtight container or wrapped tightly before placing it in the refrigerator. When reheating, ensure that the pizza is heated thoroughly and evenly to maximize the reduction of bacteria.
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Frequently asked questions
Cheese pizza should not be left out for more than two hours, according to food safety guidelines. If left out for longer, it can become dangerous to eat due to bacterial growth.
If left out for too long, cheese pizza can become contaminated with bacteria such as Staphylococcus aureus, E. coli, Salmonella, Campylobacter, and Listeria. Eating spoiled pizza can lead to food poisoning, causing symptoms such as stomach aches, dehydration, fever, chills, vomiting, and sweating.
The best way to store leftover cheese pizza is to wrap each slice individually with aluminum foil, wax, or parchment paper and place them in an airtight container or resealable bag. Store the pizza in the refrigerator, where it will remain safe to eat for three to four days. For longer storage, freeze the pizza for up to one to two months.

























