
Pizza is a beloved food for many, but it's not always the healthiest option. The number of calories in a slice of cheese and pepperoni pizza varies depending on the ingredients used, the size of the slice, and the restaurant or recipe. According to the National Heart, Lung, and Blood Institute (NHLBI), a slice of pepperoni pizza can have up to 450 calories, while a slice of cheese pizza typically contains around 710 calories. The calorie count can be influenced by factors such as crust type, with deep dish pizzas having a higher calorie count than thin crust varieties.
| Characteristics | Values |
|---|---|
| Calories in a slice of pepperoni pizza | 450 calories (as per the National Heart, Lung, and Blood Institute) |
| Calories in a slice of pepperoni pizza from specific outlets | 650 calories (Costco), 270 calories (Domino's), 300 calories (Pizza Hut), 230 calories (Papa John's), 280 calories (Little Caesars) |
| Calories in a slice of cheese pizza from specific outlets | 710 calories (Costco), 270 calories (Domino's), 300 calories (Pizza Hut) |
| Nutritional value | Pizza is not considered a healthy meal due to its high sodium and cholesterol content. It is also a source of processed meat, which has been linked to health issues. |
| Healthier alternatives | Whole-wheat crust, lower-calorie cheeses like parmesan and ricotta, adding vegetables, cauliflower pizza crust, zucchini pizza crust |
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What You'll Learn
- A slice of pepperoni pizza can contain between 200 and 450 calories
- Calories depend on pizza size, crust thickness, toppings and cheese type
- Papa John's, Pizza Hut, Domino's and Costco pizza slices compared
- Lower-calorie alternatives include whole-wheat crust and lean ham
- Pizza is high in sodium and cholesterol, and contains processed meat

A slice of pepperoni pizza can contain between 200 and 450 calories
A slice of pepperoni pizza can contain anywhere between 200 and 450 calories, depending on the size of the pizza, the ingredients used, and the crust type. For instance, a medium-sized slice of Papa John's Pepperoni Original Crust Pizza contains 230 calories, while a slice of Little Caesars' 14-inch Pepperoni Pizza contains 280 calories. The calorie count also varies based on the number of toppings, with extra toppings leading to higher calorie counts.
The calorie content of pizza is influenced by its size, as larger pizzas have more crust, sauce, cheese, and toppings, resulting in a higher calorie count. The type of crust also plays a role, with deep-dish pizzas having a higher carb content than thin-crust pizzas. Additionally, the choice of toppings can significantly impact the calorie count. For example, pepperoni, a popular but less healthy topping, contributes to the overall calorie content of the pizza.
To make pizza a healthier option, consider replacing pepperoni with lean ham to reduce sodium intake and avoid the health risks associated with processed meat. You can also opt for whole-wheat crust instead of refined flour crust and choose lower-calorie cheeses like parmesan and ricotta. Adding vegetables to your pizza boosts its nutritional value, and adventurous eaters might even try a cauliflower or zucchini pizza crust for added fibre and nutrients.
While pizza can be a treat, it's important to remember that it's not the healthiest meal option. The National Heart, Lung, and Blood Institute recommend limiting your consumption and opting for healthier alternatives when possible. For those watching their weight or calorie intake, portion control is crucial, and a smaller, healthier slice of pizza can fit within your daily calorie allowance.
Costco's pizza slices, for example, are larger and more calorie-dense than those from other fast-food chains. A pepperoni pizza slice from Costco contains approximately 650 calories, while a slice of their cheese pizza has around 710 calories. On the other hand, a slice of Domino's Large Cheese Pizza has about 270 calories, and a slice of Pizza Hut's Large Cheese Pizza contains around 300 calories. So, when indulging in pizza, it's essential to be mindful of the nutritional content and make informed choices that align with your dietary preferences and health goals.
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Calories depend on pizza size, crust thickness, toppings and cheese type
The calorie count of a cheese and pepperoni pizza depends on various factors, including the size of the pizza, the thickness of the crust, the toppings used, and the type of cheese. These variables can significantly influence the overall calorie content of the pizza.
Pizza size plays a crucial role in determining the calorie count. Typically, larger pizzas tend to have more calories per slice. For example, a slice of pepperoni pizza can range from around 230 calories for a medium-sized slice from Papa John's to 280 calories for a slice of Little Caesars' 14-inch pizza. The larger the pizza, the more slices it can yield, affecting the calories per serving.
The thickness of the crust is another factor. Deep-dish pizzas, with their thicker crusts, tend to have a higher calorie count due to the increased amount of dough used. On the other hand, thin-crust pizzas use less dough, resulting in a lower calorie intake. The type of crust can also make a difference; for instance, a whole-wheat crust may have a different calorie count than a traditional refined flour crust.
Toppings can significantly influence the calorie content of a pizza. Pepperoni, being a processed meat, adds calories and sodium to the pizza. Other toppings like sausage, bacon, or extra cheese will also increase the calorie count. On the other hand, opting for lean ham instead of pepperoni can reduce the calorie and sodium content. Additionally, loading your pizza with veggies can boost its nutritional value and potentially lower the overall calorie count.
Lastly, the type of cheese used is a critical factor. Pizzas made with mozzarella cheese tend to have a higher calorie count than those using lower-calorie cheeses like parmesan or ricotta. A blend of cheeses, such as mozzarella, Parmesan, Romano, Asiago, Fontina, and Provolone, will also impact the overall calorie content.
In summary, when considering the calorie count of a cheese and pepperoni pizza, it's essential to take into account the size of the pizza, the thickness and type of crust, the choice and quantity of toppings, and the variety of cheeses used. These factors collectively contribute to the overall calorie content, and making informed choices about these components can help individuals align their pizza consumption with their dietary preferences and health goals.
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Papa John's, Pizza Hut, Domino's and Costco pizza slices compared
A cheese and pepperoni pizza is a popular choice among pizza lovers, but the calorie count can vary depending on the restaurant. Let's take a look at the calorie content of pizza slices from Papa Johns, Pizza Hut, Domino's, and Costco to see how they compare:
Papa John's
Papa John's offers a range of pizza options, and they provide nutritional information on their website. While the exact calorie count for a slice of their cheese and pepperoni pizza is not readily available, they do provide tools to calculate the nutritional values of their pizzas.
Pizza Hut
Pizza Hut also offers a variety of pizzas, and they provide nutritional information on their website as well. Similar to Papa John's, the specific calorie count for a slice of their cheese and pepperoni pizza is not easily accessible, but they offer a nutrition calculator and detailed information about allergens.
Domino's
Domino's allows customers to build their pizzas online and provides nutritional information during the ordering process. However, the exact calorie count for a slice of their cheese and pepperoni pizza is unclear. Domino's does provide information on the nutritional content of their other menu items, such as pasta and sandwiches.
Costco
Costco's pizza slices are known for their generous size and toppings. A slice of their cheese pizza contains approximately 710 calories, while a pepperoni slice has around 650 calories. The higher calorie count in Costco's pizza slices compared to other fast-food chains is likely due to their larger size.
In summary, while specific calorie counts for a slice of cheese and pepperoni pizza vary or are unavailable for Papa Johns, Pizza Hut, and Domino's, Costco's pizza slices stand out for their larger size and higher calorie content, with their cheese and pepperoni slices containing approximately 710 and 650 calories, respectively. It is recommended to consider sharing a slice or pairing it with a salad to balance the calorie intake.
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Lower-calorie alternatives include whole-wheat crust and lean ham
A slice of pepperoni pizza can contain up to 450 calories, depending on how it's made, the ingredients used, and the size of the slice. The calorie content can be influenced by factors such as portion size, crust thickness, and the amount of cheese and oil used.
If you're looking for lower-calorie alternatives, there are several options to consider. Firstly, you can replace the refined flour crust with a whole-wheat crust or opt for other alternatives like spelt flour crust, whole-wheat pita, whole-grain tortilla, or cauliflower crust. Whole-wheat and whole-grain options provide more fibre and nutrition than refined flour.
Another alternative is to choose lean protein toppings such as ham or chicken breast instead of pepperoni. This helps reduce the sodium content and protects against the health risks associated with consuming processed meats. Lean ground turkey is another healthy option that can keep you feeling fuller for longer.
Additionally, you can boost the nutritional value of your pizza by adding vitamin-rich toppings like onions, spinach, mushrooms, olives, fresh basil, and other vegetables. If you're adventurous, you can even try making your pizza with a cauliflower or zucchini base, providing extra fibre and nutrients to your meal.
For the cheese, you can opt for lower-calorie alternatives like parmesan and ricotta instead of mozzarella. Using low-fat cheese and asking for light cheese or half the usual amount can also help reduce calories.
Lastly, be mindful of the sauce you choose. Avoid cream-based sauces like Alfredo or white sauce, as well as barbecue sauce, which tends to be high in added sugar and sodium. Instead, opt for traditional tomato sauce, either fresh or no-salt-added canned, which is high in fibre and vitamins C, K, potassium, and manganese.
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Pizza is high in sodium and cholesterol, and contains processed meat
A cheese and pepperoni pizza can contain anywhere from 250 to 300 calories per slice, depending on the ingredients and preparation methods. While pizza can be a source of certain nutrients, it is also typically high in sodium and cholesterol, and the processed meat used as a topping contributes to this.
Pizza is often associated with being an unhealthy fast food due to its high content of saturated fats and sodium. The traditional crust is usually made from refined white flour, which lacks the nutritional value of whole grains. Commercial pizza sauces may also contain added sugars and preservatives.
The cheese on pizza is a significant source of saturated fat, calories, and dietary cholesterol. While some studies suggest that cheese has little to no impact on cholesterol levels, others indicate that it can lower LDL ("bad") cholesterol when compared to other sources of fat, such as butter. Nevertheless, the type of cheese and the amount used can influence the overall nutritional profile of the pizza.
Pepperoni and similar processed meat toppings are a significant contributor to the high sodium and cholesterol content in pizza. Studies have linked the intake of processed meats with an increased risk of heart disease due to their high saturated fat and cholesterol content. For example, a meta-analysis found that those who consumed 50 grams of processed meat daily had a 42% higher risk of heart disease.
While pizza may have a reputation for being unhealthy, it can be made healthier by opting for high-quality, fresh ingredients. For instance, an authentic Italian-style pizza prepared with higher-quality ingredients, such as fresh tomato sauce, can be a source of antioxidants like lycopene, which has potential health benefits. Additionally, choosing healthier toppings, such as vegetables, and using whole-wheat crust can also enhance the nutritional value of pizza.
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Frequently asked questions
According to the National Heart, Lung, and Blood Institute (NHLBI), a slice of pepperoni pizza can have up to 450 calories. However, this may vary depending on the size of the slice and the ingredients used.
Yes, replacing pepperoni with lean ham can help reduce sodium intake and the dangers associated with eating processed meat. Additionally, opting for a whole-wheat crust and lower-calorie cheeses like parmesan and ricotta can also reduce the overall calorie count.
A slice of pepperoni pizza from Costco's food court contains approximately 650 calories. The higher calorie count is primarily due to its larger size and generous toppings.
The calorie count of a pepperoni pizza slice can vary across different restaurants. For example, a medium-sized slice of Papa John's Pepperoni Original Crust Pizza has 230 calories, while a slice of Little Caesars' 14-inch Pepperoni Pizza has 280 calories.
Yes, the Centers for Disease Control and Prevention recommends substituting a slice of pepperoni pizza with a bowl of minestrone soup, which has less than half the calories and provides additional nutrients from vegetables.
























